Ruby is a Jewelpet, a creature whose eyes are jewels, living in the magical world of Jewel Land. In order to find a partner, Ruby travels to the human world and meets Sakura Akari. The two form a pact to compete together in a magic contest being held in Jewel Land.

Kurata Sana is a frenetic eleven-year-old child actress with an extremely overprotective agent, a mother who is an eccentric award-winning author, and a burning desire to do well in school. However, as much as she wants to be a good student, the antics of the boys in her class make learning impossible, according to Sana anyway. And in her eyes, Hayama Akito is the worst offender of them all. A junior-high war of the sexes ensues, and Sana eventually realizes through the chaos that Hayama may not be the devil boy she's made him up to be.

The Trump Kingdom is a magical world where everyone's hearts live happily with the guidance of their ruler Princess Marie Ange. However one day, a evil force known as the Jikochuu attacked the Kingdom. But a warrior who served Marie Ange, known as Cure Sword, fended the Jikochuu by herself before being sent the human world with her fairy partner to find the missing princess. The Cure Sword also brought with her three other fairies who are to find three chosen girls to be her allies. One of the fairies, Charles, finds a girl named Mana Aida who is her school's student council president. Whilst visiting the Clover Tower's observatory during her school's orientation day, Mana encounters a Jikochuu who attempts to manipulate her heart but being found by Charles as he gives her the power to become Cure Heart. Joined by Cure Diamond, Cure Rosetta and Cure Sword, the Dokidoki PreCure must fight to protect everyone's hearts from the Jikochuu.

Chocolat and Vanilla are little witches. They are good friends as well as rivals for the next queen candidate. To decide who is eligible for the next queen, they came to human world. They compete with each other by collecting hearts of men. Which of the two will become the queen?